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TLR3KO mice produced comparable levels of IFN-γ following LCMV challenge (Figure 5C) confirming that this receptor does not play a central role in the response to LCMV.
Similarly, as early as 2 wk after infection, the splenocytes from the MGL1−/− and MGL1+/+ mice produced comparable levels of IL-4).
Both WT and RASSF1A−/− mice produced comparable levels of TNF-α in the serum following LPS injection; however, since RASSF1A−/− mice exhibited an attenuated inotropic response to TNF-α, this could account for the reduced contractility exhibited by RASSF1A−/− mice following LPS injection (see Supplementary material online, Figure S5 ).
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Our IgGMOG samples obtained from adult NMO patients, and the anti-mouse MOG-specific monoclonal antibody, both recognized mouse MOG in frozen brain sections, and produced comparable LFB loss without inflammation.
In the animal model, vancomycin and linezolid monotherapies produced comparable bacterial decreases in mice infected with each strain but linezolid achieved higher rates of blood sterilisation.
At 16 weeks post-infection, Pycard−/− and Nlrp3−/− animals produced comparable if not enhanced levels of cleaved IL-1β compared to wild type mice (Figure 4B, bottom panel).
Cilnidipine and nimodipine produced comparable beneficial effects in restoring immobilization stress subjected mice.
While EE and TAM produced comparable levels of LEH induction (~2.6-fold) in the mouse at 72 hrs, TAM treatment in the rat elicited a significantly greater LEH increase (p < 0.05, 4.4-fold for TAM and 2.6-fold for EE).
The PCO and STRUCTURE output produced comparable results.
Risk classification using their BCI algorithm likewise produced comparable results.
Preliminary immunoblot studies indicated that adding 20 µg/ml of rhTSP-1 to platelet releasates of Thbs1−/− mice produced TSP-1 levels comparable to those in platelet releasates from WT mice and humans (Fig. 2E).
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