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However, the heterogeneity in the timing and extent of disease progression in C3HeB/FeJ mice presents a challenge for routine use as a model for evaluating drug efficacy.
In particular, the C57BL/6J strain of inbred mice presents a higher degree of resistance to T. congolense than the A/J and BALB/cJ mouse strains [ 10, 12].
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Genetically engineered mice present a wealth of disease models particularly interesting for the neuroscience community.
Genetically modified mice present a useful model as tumor development can be studied both during embryonic and post-embryonic development (Fig. 5).
TgRCAN1 mice present a marked disruption of the learning process in a visuo-spatial learning task.
In conclusion, the testis and epididymis of SP mice present a reduced concentration of αSNAP.
We have previously described that hyh mice present a heterogenous neuropathological and clinical phenotype [12].
During schistosomiasis, gal3−/− mice present a biased Th1 cellular and humoral immune response [12].
Interestingly, fasted N2KO mice presented a significant, 5.16-fold (*p≤0.05, T value = −2.99, df = 4) increase in serum leptin levels compared to WT mice.
We demonstrated for the first time that the peritoneal macrophages and the cell types present in the cecal tissue from HF fed mice present a M2b polarization.
SP mice present a preserved general motor activity [12] and are able to copulate; a vaginal plug was normally observed in their female partners.
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