Sentence examples for mice pointed to from inspiring English sources

The IMERV deficiency and the missing splenic PrP up-regulation of 129/Sv mice pointed to a possible dependence of PrP up-regulation on MLV activity.

Altered sympathetic outflow to BAT and reduced food intake in Bmp8b −/− mice pointed to a possible central role of BMP8B.

In vivo transport experiments using knockout mice pointed to the role of this carrier in limiting the CSF concentration of drugs such as etoposide in the CSF [ 16].

PCR array analysis of the mandibular bone of caspase-7-deficient versus wild-type mice pointed to a significant decrease in mRNA levels for Msx1 and Smad1 in early bone formation.

Analysis of RANK- and RANKL-deficient mice pointed to a role for this pathway in the mammary gland during pregnancy [ 5] and in mammary carcinoma metastasis to the bone [ 6].

Furthermore, data from wt mice point to an ongoing alveolarization during adult life in C57Bl/6NCrl mice.

In conclusion, we have identified genes whose expression differs between the peak and trough of 24-hour circadian BP in BPH/2J mice, pointing to mechanisms responsible for diurnal variation in BP.

Indeed, Waeckel et al. demonstrated that in CXCR3-deficient mice, fewer T cells and monocytes/macrophages accumulated after ischemic injury and that transfer of wildtype bone marrow-derived mononuclear cells restored the impaired neovascularization in CXCR3-deficient mice, pointing to a leukocyte recruitment-dependent mechanism contributing to CXCL10's angiostatic effect in vivo [20].

Ablation of CYP7B1 (that redirects 25OHC by conversion to the EBI2 ligand 7α,25OHC) increased ATH severity in mice, pointing to a specific predisposing effect of 25OHC itself [ 103].

Moreover, most strikingly, FAP deficiency broadly ameliorated cartilage degradation in hTNFtg mice, pointing to an important role of FAP in cartilage destruction in RA.

Interestingly, Msi1 protein levels increased with age in adult mice, pointing to the possibility that stress associated with normal aging can upregulate Musashi levels.