Fewer mice persisting at high diversity sites across seasons, indicates that these sites are less likely to have infected individuals remaining to maintain SNV in the population.
Our previous work indicates that significant disruption of adulthood neurotransmission in response to CAPs exposure in mice persists at least to almost 1 year of age (Allen et al. 2014a, 2014b).
Differences in the functional recovery between control and conNrg1 mutant mice persisted until 56 days post-injury, but became less pronounced at late stages.
However, in the group sacrificed 2 h following propofol, despite the recovery of the righting reflex in all of these mice, hippocampal tau hyperphosphorylation persisted at the AT8 epitope and was 195±31% of control (Fig. 3A1).
Compared to WT mice, airway eosinophilia induced by RWE challenge persisted at day 10 in Ifng KO mice (Figure 6B), indicating a critical role of Ifng in regulating allergic airway inflammation.
In contrast to LPS responder mice, both BRD509 and GIDIL2 strains persisted at higher levels in LPS non-responder animals.
Kidney infection persisted at 6 days in HeN mice (median: 92.0 CFU/kidney pair, n=24) (Fig. 2A).
Although continued elevation of IL-8 and G-CSF concentrations and slow wound healing persisted at 30d, other biomarkers in the same mice had recovered to normal values in the surviving mice.
However, although the CD8+ T cells persisted at a high frequency in the livers of mice treated with the unregulated vector, they decreased substantially 3 weeks post-injection in IDLV.142T-treated mice (Fig. 5A).
Tumor size and mice health was monitored for the subsequent 60 days post-treatment, and mice were sacrificed when tumor size exceeded 1500 mm, or after completion of the experiments if tumors persisted at 60 days after treatment.
