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The high occurrence of reelin and (to a lesser extent) VIP indicates that the vast majority of GFP-labeled interneurons in GAD65-GFP mice originates from the CGE.
Previous reports have suggested that the majority of GFP-labeled interneurons in GAD65-GFP mice originates from the caudal ganglionic eminence (CGE) [11], [20].
Our data strongly suggest that the hydrocephalus phenotype in Pkd1 mutant mice originates from the third ventricle, the first compartment to develop ciliated ependyma, and subsequently expands to the lateral ventricles.
These results unequivocally confirm that the observed phenotype in DKO mice originates from CB2R activation.
To clarify if the accumulated CE in HSLiKO mice originates from dietary sources we gavaged mice with [H]cholesterol.
Therefore, the appearance of MC1 or AT8 reactivity in TauRDΔK mice originates from endogenous mouse Tau, which has been transformed to a pathological state, triggered by exogenous TauRDΔK.
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We also thank Dr. Michael Hastings (LMB, University of Cambridge, UK) for supplying the original breeding stock of PER2::LUC mice (originating from Prof. Joseph Takahashi (University of Texas Southwestern Medical Centre, USA) and Prof. Anthony Harmar (University of Edinburgh) for original breeding stocks of Vipr2−/− mice.
ENU-treated mice originating from a B6 genetic background, were outcrossed to C3H mice for genotyping.
Our studies have revealed population substructure among CD-1 mice originating from more than one facility.
All F. tularensis strains (n = 8) used to infect mice originated from human cases of tularemia (Table 1).
To address these mechanisms, we analyzed TB progression in a panel of genetically heterogeneous (A/SnxI/St) F2 mice, originating from TB-highly-susceptible I/St and more resistant A/Sn mice.
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