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In acute study, we firstly tested median lethal dose (LD50) in mice of three cadinene sesquiterpenes 2-deoxo-2- acetyloxy -9-oxoageraphorone (DAOA), 9-oxo-agerophorone (OA) and 9-oxo-10,11-dehydro-agerophorone (ODA) from Eupatorium adenophorum (Ea).

By 12 weeks of age, mice of three genotypes exhibited no significant difference in click-evoked ABR thresholds.

Testing was carried out using male adult mice of three different strains: Swede mice: Three mice of the strain B6.Cg-Tg APPswe,PSEN1dE9)85DB6.Cg-Tg APPswe

Our data show that the three v-rDNA regulatory groups are present in six mice of three strains, which strongly suggest that their regulation is not randomly determined.

To determine if the status of Fto has an effect on the response to diet, both male and female mice of three genotypes (Fto+/+, Fto+/Δ and FtoΔ/Δ) were fed on high fat diet (60 kcal % fat) from 4-week-old on for 10 weeks.

RNA extracted from the mice of three litters (on average eight pups per litter) of the same genotype was pooled and used for microarray analysis.

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CD1Nu/Nu mice of eight weeks were purchased from Charles River (Sulzfeld, Germany).

I also tested the relative use by mice of four microsite types: CWD, pits, woody brush, and open ground.

Delivery into mice of two HEV ORF2 genes via a papillomavirus VLP was very effective in the induction of anti-HEV antibodies.

Adult mice of two different genetic backgrounds (BALB/c & C57BL/6) were analysed.

Male mice of five inbred strains, C57BL/6JOxjr, BALB/cOxjr, DBA/2OlaHsd, 129S6/SvEvOxjr and C3H/He NHsd were used.

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