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Interestingly, lacrimal glands contained approximately 10 times more CXCL13/mg tissue measured by ELISA than did salivary glands of female NOD mice of comparable age (data not shown).
Sections obtained from other control and ablated mice of comparable ages were also used for double-labelling studies to cross-validate the developmental patterns of expression of lacZ and HSV-TK reporters in GPT neurons.
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Increased T cell proliferation in vitro or increased expansion of T cells in vivo in HLA-DR3.IFN-γ−/− mice was probably not due to increased expression of HLA-DR3 molecules in HLA-DR3.IFN-γ−/− mice because of comparable numbers of CD4+ T cells were present in both groups of mice in both thymus and spleen (Fig. 7).
At two months, AC3−/− and AC3+/+ mice are of comparable weight.
Following short term as well as long term OVA challenges in OVA sensitised mice, AHR of comparable magnitude developed.
Pre- or non-diabetic NOD mice of a comparable age but with incompletely characterized glucose tolerance had a somewhat increased proportion of β-cells with elevated DNA content (2.9%, range 1.8 4.4).
This seems unlikely, however, because behavioral improvement due to androgen ablation was not observed in mice of a comparable age until 3 months following castration (Chevalier-Larsen et al., 2004) and elevated testosterone levels were restored in month four, following pellet re-implantation.
The percentage of Treg in the spleen of tolerant mice was comparable to naive mice of corresponding age (10.1% vs 9.1% at day 20, 11.4% vs 10.3% at day 100, p>0.05 Figure 3B).
Human and mouse embryos are of comparable size but the adult human is around 3,000-fold 3,000-foldn an adulargerse and lives 40 thans longer.
The severity of the clinical signs and histopathological lesions, the extent of weight loss, lung virus titers and mortality rates of these mice was comparable of those that were immunologically naïve prior to infection with IAV IND/05 (group 4) or that were vaccinated against IAV HK/68 virus, but not subsequently infected with IAV HK/68 virus (group 5).
The mammary gland of mice is comparable with that of humans in that it consists of a converging branched epithelial ductal network embedded within a stromal mammary fat pad [ 4].
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