Mice used in this study were athymic nude mice obtained from Taconic (Hudson, NY, USA).
Spleens were isolated from OT-I (CD8+) and OT-II (CD4+) transgenic mice (obtained from the Walter and Elizabeth Hall Institute of Medical Research, Australia).
For organismal ageing, 2 and 18-months-old female BALB/C mice obtained from National Institute of Nutrition (Hyderabad, India) were used.
To study the characteristics of iCre-mediated recombination, mice carrying the Fgfr3-iCre-ERT2 transgene were bred with the ROSA26tm14 CAG-tdTomato ROSA26tm14 CAG-tdTomatoer mice (obtained from the Jackson Laboratory)20 to genereporterr3-iCre-ERT2;Ai14(tdTomice) animals.
This work was also made possible through use of the Manchester Gnotobiotic Facility that was established with the support of the Wellcome Trust (grant no. 097820/Z/11/B), using founder mice obtained from the Clean Mouse Facility, University of Bern, Switzerland.
The antitumor efficacy of AgNPs in vivo was assessed by using Ehrlich ascites tumor model in mice obtained from the National Cancer Institute-Egypt, in ascetic form and was maintained by serial transplantation.
Population substructure and phenotypic differences were observed among CD-1 mice obtained from different breeding facilities.
Female C57B6 mice obtained from Charles River (6 8 weeks old; 20 gr.
We also observed significant differences in phenotypes for mice obtained from different facilities.
Briefly, the mice obtained from Jackson Laboratory were maintained on a C57BL/6 background.
We first tested murine embryonic fibroblasts (MEFs) from src-/-yes-/-fyn-/ triple knockout mice (obtained from ATCC).
