But if they give the same gene to another mouse strain, called C57BLKS/J, the mice not only grow fat but are dead of diabetes in five months.
In recent months, researchers have discovered that a prion from hamsters, thought never to infect mice, not only replicates profusely in mice but it does so without producing disease symptoms.
The impaired TCA cycle activity in mice with reduced or null ERRα activity while treated with rapamycin suggests that these mice not only have a decreased capacity to oxidize lipids but the accumulation of citrate is reoriented toward lipid biosynthesis.
In conclusion, the present study demonstrated that oral administration of B. breve A1 to AD model mice not only improved cognitive dysfunction but also suppressed the expression of inflammation and immune-reactive genes induced by Aβ.
We found that depletion of Nlrp3 in mice not only increases their survival in sepsis but also inhibits sepsis and inflammation-mediated muscle atrophy.
Interestingly, ATM−/− Gadd45a−/− mice not only showed a higher incidence of T-cell lymphoma compared to ATM−/− mice (Fig. 5A), but also developed acute myeloid leukemia (AML) (Fig. 5B and 5C).
Work using mice not only supports the results found using cell lines, but when extrapolated to humans, indicates that an efficacious dose of tocotrienols could be consumed from the diet ([He et al. 1997]).
Two weeks later, Ferrari found that the damaged muscle areas in nine mice not only showed signs of recovery but also had numerous blue nuclei throughout--indicating that these new cells had started out as transplanted bone marrow cells.
Mucosally vaccinated mice not only survived, but had little morbidity and reduced lung virus titers.
These mice not only showed induction of a strong CD4+ and CD8+ T cell response following immunisation but also acquired strong resistance to virus infection.
Thus, vascular leakage of EB and albumin was detected in Naglu mice not only at late stage of disease but also concurrent with early disease symptoms.
