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The immunoPET images (Figure 7) and time-activity curves (TACs; Figure 6) show that in PU-H71 treated mice, no difference was observed in either the mean or maximum T/M ratios between BT-474 and MDA-MB-468 tumors.
To confirm the specificity of the control by TLR4 of the induction of anti-LPS IgG3 antibodies we followed the induction of natural IgG3 antibodies to LPS in TLR2-deficient mice: no difference was seen in their levels when compared to matched controls (Figure 2D).
Student Newman-Keuls (SNK) post hoc analyses revealed that for R mice the preference score from the reinstatement test session was significantly higher than that on the last day of extinction (q = 11.508, p<0.001), demonstrating robust reinstatement, whereas for NR mice no difference was observed (q = 0.513, p>0.05).
In male mice no difference in carcinoma development was found between the mouse groups.
In treated mice, no difference in CXCL-10 levels was noted on day 5 PoI, compared to control levels.
While endothelium-dependent relaxation was markedly reduced by diabetes in Agtr2+/+ mice, no difference between control and diabetic group has been shown in Agtr2-/ mice.
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After three feedings, 1 week apart, 1 g per mice, no differences were detected in the growth rate or behavior of the animals fed with these three types of spinach.
In the MRL/MpJ mice, no differences in bone density, subchondral bone thickness, or histologic grading of cartilage degeneration were seen between fractured and contralateral control limbs.
However, after immunization of C57BL/6 mice, no differences were detected between modified NP and wild-type NP (NPwt), since NPwt already induced optimal CD8+ T cell responses.
Again, although significant reductions of nucleosomes of DNase-treated mice were seen in BALF (P = 0.002) compared to untreated mice, no differences were seen in bacterial burdens in BALF, lung, blood, or liver nor local or systemic inflammatory cytokine levels 72 h post-infection (data not shown).
In KO mice, no differences were noted in the numbers of splenic or thymic CD3, CD4, CD8 or regulatory T cell populations or activation marker expression after stimulation (not shown), eliminating developmental differences between WT and KO mice.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com