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The incorporation of a time delay forces retention of trial-unique spatial information (i.e., the mice must remember which arms were visited in phase 1 in order to successfully complete phase 2, increasing the spatial working memory load).
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Although on the surface this seems counter to the situation in mice, one must remember that studies of aged humans are confined to examination of peripheral blood B cells.
"So far so good but we must remember that mice are not men (or women)." Professor Francis Drobniewski, Director of the Health Protection Agency's National Mycobacterium Reference Laboratory said: "This is an exciting and thoughtful piece of research.
Animals like gerbils and mice also make great pets, but one must remember that they need stimulation as well.
One must remember that the mdx mouse is relatively healthy in comparison with human sufferers of DMD.
However, one must remember that in the 11β-HSD2−/− mouse there is no 11β-HSD1 substrate (11-dehydrocorticosterone) and therefore this will have ramifications for brain function, albeit perhaps most notably with ageing.
Even though we argue that the Sgcg−/− D2 mouse is a better model of human muscular dystrophy we must remember that it is still a model.
However, we must remember that this up-regulation is occurring in two different mouse models of SMA at a pre-degenerative time point, prior to any NMJ loss.
One must remember, however, the aspects of very distinct differences in innate and adaptive immunity that exist between mice and men [ 14].
Must remember.
I must remember that.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com