Sentence examples for mice modelling from inspiring English sources

In Sod1 mutant mice modelling amyotrophic lateral sclerosis (ALS), extracellular free-floating mitochondria have been described in the brainstem.

These findings confirm that loss of CDKN1C function causes somatic overgrowth in mice, modelling this key aspect of BWS.

41 A clearer understanding of the underlying causes of inherited arrhythmias has arisen as a result of basic research, particularly from engineered mice modelling genetic abnormalities.

For example, Spg20 −/− mice, modelling Troyer syndrome, show progressive gait defects and increased lipid droplet numbers in adipose tissue (Renvoisé et al., 2012).

Several immunodeficient mice modelling DMD are available, including the nude/mdx mice [ 88], lacking the T-cell compartment, the SCID-mdx mice [ 89], lacking both T and B cells, and the recently described NSG-mdx4CV [ 90], and Rag2−IL2rb−DMD− mice [ 91], in which the NK cell activity is also defective.

Pharmacokinetic (PK) analysis of the different application protocols used in mice modelling CJD as well as Parkinson's disease (vide infra) revealed that anle138b has an excellent oral bioavailability and excellent blood brain-barrier penetration, and that concentrations shown to blood brain-barrierCA assay were obtained in the brain (Fig.  5).

Firstly, gastric cancer-bearing nude mice models were prepared.

MCF-7/DOX and MCF-7 xenograft mice models were established.

Only PS1xAPP mice model accumulated Abeta plaques.

PB contributed important knowledge (granuloma mice model).

EH performed experiments (granuloma mice model).