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Possibly, temporally restricted deletion of LGI1 using inducible Cre transgenic mice may permit the differentiation of defects in synaptic transmission and/or cellular excitability due to prenatal or postnatal neuronal development, and those due to a lack of LGI1 in the adult.
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The combination of siRNA, the SB transposon, and an accurate transgenic mouse model may permit evaluation of this approach in preventing the pathogenesis associated with expression of mutant Htt.
These technologies may permit successful fetal surgical procedures.
This may permit reasonable predictions of individual patients' recovery rates.
Convergence may occur over considerable distances and so may permit virtually straight flight while climbing.
This may permit recombination and formation of unstable translocations.
However, acid treatment may permit intracellular binding.
The use of kidneys from ECD may permit more transplantations.
Mitotic exit may culminate in apoptosis in the subsequent interphase or may permit cell survival.
Since even modest handling of mice may induce alterations in heart rate [ 6], each mouse was permitted to acclimatize for 10 min prior to collection of baseline data.
Ileitis in SHIP-deficient mice may result from a deficit in mucosal T cell function that permits inappropriate granulocyte monocyte responses to commensal organisms and luminal antigens culminating in the inflamed states observed in the ileum of SHIP-deficient mice.
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