Although infection results in eventual death of all mice, the majority of susceptible mice develop neurological symptoms between days 6 10 post-infection that closely mimic human CM.
In contrast to the female mice, the majority of male mice did not begin to develop anti-dsDNA autoantibodies by 30 wks of age.
There was a huge difference between 129S6/SvEv and C57BL/6J WT mice: the majority of 129S6/SvEv mice (both males and females) did not turn downward at all during the test trials (Fig. 3).
Phenotypic analysis of T cell populations in organs of the FtDKO mice reveal that similar to WT mice, the majority of T cells in the spleen and lung were naïve (CD44lo and CD62Lhigh) (Figure 1B and data not shown).
Compared with the moderate LC3 staining in control or tgWT mice, the majority of the spinal cord motor neurons of tgMT mice showed a significant increase in LC3 fluorescence, which was well-colocalized with intracellular Seipin aggregates.
Similar to B6 mice, the majority of the remaining CD94-NKG2-expressing cells from CD94Tg/– mice were NKT cells and T cells (Fig 1A).
Interestingly, whereas in naïve mice the majority of induced Tregs were CD4+ and produced TGFβ, in primed mice the induced Tregs were CD8+ Tregs and the response involved Fas-mediated deletion of Teffs [ 87].
Besides Stx-t and Tfr knockout mouse, the majority of knockout-mouse models for iron homeostasis show hereditary hemochromatosis or anemia.
In normal mice, most fenestrations are irregular holes with a relative large size (Fig. 2A) while, in As III -exposed mice, As III -exposedenestrations appear as approximicely round holes and majoritythem are relatively smaller than thofe in normal ones (fenestrations
In wild-type mice, the majority of 99mTc-SER-4 monoclonal antibody cleared from the blood with a half-life of 167 min and was located predominantly on Sn+ tissues in the spleen, liver and bone marrow.
