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Newborn mice (less than 24 hours old) were obtained from pair-wise mating of female and male BALB/c mice.
In these experiments, all transfers were carried out using neonatal mice less than 24 hours old to mothers that had delivered their own litters also within the previous 24 hours.
It is interesting that the percentage of peripheral blood MBC which we observed in mice (less than 5% of total B cells) during primary and secondary infection is lower than that typically found in humans.
We observed that kidneys from mice less than two weeks old predominately presented dilated tubules and cysts, whereas mice more than 18 days old also developed hyperplasia and renal cell carcinoma in their polycystic kidneys (Figure 3G J).
In mice less than 3 weeks old, the effect was much less marked than in adults.
The new figure shows that results hold in pcd mice less than 50 days old, before extracerebellar degeneration.
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Like Fmr1 knockout mice, social approach also was unaltered in GSK3 knockin mice in the presence of a single stimulus mouse, and GSK3 knockin mice approached a novel second mouse less than did wild-type mice.
While mouse models may not be fully representative of the injured human liver and human hepatocytes tend to engraft mice less efficiently than mouse hepatocytes, valuable lessons have nonetheless been learned from transplanting human hepatocytes into mouse models.
This analysis revealed that Eps8KO mice weigh less than WT mice and are partially resistant to aging and diet-induced obesity.
Immune-stimulated macrophages from APOE3/0 mice demonstrated an increased inflammatory response compared to APOE3/3 mice, but less than in APOE4/4 mice.
The intensity and amount of TRAP staining in ZAS3−/− mice were less than ZAS3+/+ mice at both ages.
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