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Half of the mice lacked a gene that is needed to make adenosine receptors, which are found on major nerves.
Half of the mice lacked a gene that is needed to make adenosine receptors, which are dotted along major nerves.
In contrast to other models of retina-specific Vhl inactivation [19, 20], rodΔVhl mice lacked a strong vessel phenotype.
Using an experimental mouse strain that is highly susceptible to the synaptic and cognitive impairments of Alzheimer's disease, Shatz and her colleagues showed that if these mice lacked a surface protein ordinarily situated very close to synapses, they were resistant to the memory breakdown and synapse loss associated with the disorder.
The mice lacked a gene called Bim, which codes for a protein in the stress-induced pathway.
But six of nine PlGF-deficient mice lacked a continuous bone and instead had an unstable, lumpy mass of soft cartilage at the wound site, Carmeliet's team reports today in the Journal of Clinical Investigation.
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For instance, myoblasts from mice lacking A-type lamins that exhibit signs of muscular dystrophy plate with high viability and proliferate normally, but ultimately have impaired differentiation [39].
In obese mice lacking A-FABP, dyslipidemia and peripheral insulin resistance are improved and β-cell function is preserved (11).
Meanwhile, Pycard−/− mice lacked an additional mechanism to form or maintain granulomas thereby compromising their resistance to Mtb infection.
d'Anglemont de Tassigny, X. et al. Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene.
This was not apparent in mice lacking a functional NOS-2 gene.
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