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Giving shots to countless numbers of mice is impractical, of course, but the vaccine can also be given in food, as is done to fight rabies.
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A proper validation experiment to demonstrate that the DMRs we have identified are associated with imprinted methylation and gene expression requires being able to trace the parental origin of the methylated and expressed alleles in multiple members of the same family, which can be done in mice but is impractical and ethically impossible to do across multiple tissues in humans [ 37].
The use of a liquid ethanol diet offers a reliable method for the induction of alcohol dependence in mice, but this approach is impractical when conducting high-throughput pharmacological screens or when comparing multiple strains of genetically engineered mice.
It is impractical".
But this is impractical.
That, however, is impractical.
"Changing players is impractical.
This is impractical.
Electoral officials worry that is impractical.
Heroism is impractical; tragedy unprofessional.
And it is impractical, Mr. Nulty said.
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