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These results suggest that the lung phenotype of Cby−/− mice is attributable, at least in part, to reduced proliferation rather than increased apoptosis or alveolar septation defects.
It can be concluded that the severe and identical clinical phenotype in both humans and mice is attributable to the complete absence of the CD18 protein.
Together with our control experiments (see Experiments 2 6), the data strongly suggest that strain-dependent variation in the social approach phenotypes of early-adolescent mice is attributable to a genetic influence on a specific, social-motivational process.
To determine whether the reduction in contextual fear memory of neurabin KO mice is attributable to changes in pain sensitivity to the foot shock, we measured acute sensory thresholds in the hotplate and tail-flick tests.
The inhibition of AIF translocation from mitochondria to nuclei in the cathepsin K knockout mice is attributable to its inhibition of PARP.
Rreb1 binds and represses expression of the p16(Ink4a) promoter, and the development of pristane-induced plasma cell tumors in Balb/C mice is attributable to a polymorphism in this Rreb1 binding site (Zhang et al., 2003).
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The exaggerated lipid accumulation in sucrose-palmitate-fed mice was attributable to a disproportionate rise in hepatic de novo lipogenesis.
The increased memory cells in Cdc42−/− mice are attributable to enhanced proliferative renewal.
Taken together, our data suggested that the reduced body weight of Rcan2−/− mice was attributable to reduced food intake.
Once again the parasite burden was lower in BALB/c mice confirming that the poor expansion of P.berghei in BALB/c mice was attributable to intra-hepatic factors.
Similarly, the weight difference between female AC3−/− and AC3+/+ mice was attributable to a large increase in fat mass (Figure 2B).
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