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Studies in γc/RAG2 knockout mice indicated that rejection of N2A cells expressing a combination of IL-2 and IL-12 was an immunological phenomenon.
In vivo studies in mice indicated that the coated polymer MNs continuously delivered drugs, and the skin recovered without any injuries.
Cytotoxicity and bioimaging studies by L929 cells and living mice indicated that the probes were low cytotoxicity, cell permeable and suitable for detecting ClO− in biological environments.
Biodistribution experiments using SCCVII-bearing mindicatedathatthat GPU-201 showed comparable tumor uptake and a significantly longer retention in tumors compared with BSH.
The tissue distribution studies in mice indicated that PTX-mPEGOSC2000M micelles were phagocytized less than PTX-OSC micelles by reticuloendothelial system (RES).
Cytotoxicity and bioimaging studies by L929 living cells and living mice indicated that the probes were negligible cytotoxicity, cell permeable and suitable for detecting Hg2 + in biological environments.
Further, in vivo antitumor study with xenograft nude mice indicated that compound 5 inhibited the growth of MDA-MB-231 cells and showed lower toxicity than etoposide (VP16).
Human fibroblast cell-based assay and in vivo analysis in mice indicated that two improved IL-17RA mutants efficiently inhibit the secretion of IL-17A-induced proinflammatory cytokines.
Previous studies in mice indicated that G protein immunization resulted in antibody and Th2-type response and failed to induce MHC I-restricted CD8+ T-cell response.
Further histological analyses in CX3CR1EGFP/+ CCR2RFP/+ transgenic mice indicated that MSC/IL-13 significantly decrease the number of resident microglia and increase the number of alternatively activated macrophages.
Dosimetry estimates using FCH biodistribution data in mice indicated that the kidneys are radiation-dose-critical organs for FCH.
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