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I concluded that the concentration of extracellular diffusible Aβ1 42 in CRND8 mice increases from 160 pM to 425 pM as CRND8 mice age from 3 to 6 months.
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The brain dopamine levels in the KI mice increased from 9.39% of the levels in wild-type mice at 2 weeks of age to 37.86% of the levels in wild-type mice at 8 weeks of age.
The ratio of striatal WIN binding in vaccinated mice versus unvaccinated MPTP-treated mice increased from 4 to 21 days, suggesting that the CFA-induced responses promoted a greater rate of neurorestoration.
In the long-term, the proliferative responses of splenocytes from heterologously vaccinated mice increased from 9600±578.8 cpm to 11546±610.8 cpm after challenge infection suggesting that DNA-prime/Protein-boost regimen induced long-term cellular responses compared to all vaccinated mice (p<0.001) (Figure 2D and H).
The weight of the lovastatin-treated group B mice increased from 16.2±0.4 g at the time of lovastatin treatment to 17.1±0.4 g during the of 6-day lovastatin treatment period and then decreased 0.9±0.2 g after 48 h after the Y. pestis challenge, gradually increasing to 18.9±0.4 g by the end of the 10-day observation period.
VZ/SVZ total area in ablated mice increased from 1.40±0.20 to 2.76±0.26 mm between E12 E18, a cumulative growth of 97%.
Pallial thickness in ablated mice increased from 0.19±0.01 to 0.72±0.04 mm between E12 P4, a measured cumulative growth of 279%.
VZ/SVZ unscarred volume in ablated mice increased from 0.20±0.02 to 0.79±0.13 mm between E12 and E18, a measured cumulative growth of 295%.
VZ/SVZ thickness in control mice increased from 0.123±0.007 to 0.189±0.005 mm between E12 and E18, a cumulative growth of 54%.
Pallial total area in ablated mice increased from 2.9±0.3 to 19.3±2.1 mm between E12 and P4, a measured cumulative growth of 566%.
Pallial unscarred volume in ablated mice increased from 0.36±0.04 to 5.86±0.84 mm between E12 and P4, a measured cumulative growth of 1528%.
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