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Topical applications of 100 mg of Dermabase, Dermovan, Eucerin Original Moisturizing Cream (Eucerin), or Vanicream once a day, 5 days a week for 17 weeks to these high-risk mice increased significantly the rate of formation of tumors and the rate of increase in tumor size per mouse.
During the 16 week experimental period the body weight of both HFBT and HFP fed mice increased significantly compared to the chow-fed mice (Figure 1A).
Concomitantly, the number of BrdU+ cells in ibuprofen-fed FeCγ25 mice increased significantly and were comparable to those seen in wild-type mice (Fig. 5B, C).
When the training was conducted for 5 consecutive days, the OKR gains of both the wild-type and mutant mice increased significantly with the number of training sessions (session effect, F 9,207) = 82.1, p<0.001; Fig. 6E).
The signal intensity from the liver area of STZ-treated mice increased significantly each day thereafter (23.30±0.66×104, 47.0±1.85×104, 58.5±2.30×104 and 62.60±2.19×104 photons/second respectively), resulting in a statistical difference from the control mice on days 2, 4, 6, and 8 (p = 0.044, 0.046, 0.012, and 0.031 respectively).
By contrast, the number of apoptotic cells in neurospheres derived from Beclin 1 +/− mice increased significantly relative to the wild-type.
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New proliferating progenitor cells expressing Id3, identified by Sox2 and BrdU (1 hour pulse), were present in control mice but increased significantly in PC3/Tis21-null mice (1.56-fold increase; BrdU+/Sox2+/Id3+, p = 0.0008; Figure 8B, F).
However, the AHR of EO mice was increased significantly relative to AO mice, demonstrating an ETS-dependent exacerbation of AHR to initial allergen exposure.
Our results showed that the heart mass index, left ventricular mass index and hydroxyproline content in the left ventricles of the aged mice were increased significantly compared with the adult mice, indicating that left ventricular remodeling occurs with aging.
The hair density and length of Eclipta alba treated mice were increased significantly (P > 0.001) than control mice.
As previously observed in hairless mice, murine IgE levels remained unaffected in ethanol-treated mice and increased significantly in the oxazolone-treated group.
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