Sentence examples for mice inactivated systemically from inspiring English sources

Consequently, mice inactivated systemically for Slc30a8 display profound changes in insulin crystal formation and secretory granule morphology [ 14, 15], consistent with the lower zinc-transporting activity of the transporter isoform encoded by the risk allele [ 15].

Thus, mice inactivated for LKB1 by Pdx1.

To determine the role of Cdc42 in heart development, we created a mouse line by crossing Cdc42/flox mice with MLC2a-Cre mice, which inactivated Cdc42 in the embryonic cardiomyocytes [22].

The H-2Kb and H-2Db genes in HLA-B7 mice were inactivated by homologous recombination.

In experiment 3, cartilage-specific ERα inactivated mice and WT littermates were used.

Importantly, no adverse effects were seen in muscle of wild-type mice injected systemically with scAAV.hSGCB.

Oral administration of murine IFN-γ significantly elevated the survival of mice challenged systemically with a lethal dose of encephalomyocarditis virus (Tovey and Maury, 1999).

However, one caveat to this analysis is that these mice are systemically deficient in IFNAR1.

In contrast, none of the mice receiving systemically applied antiretroviral PrEP exhibited viral DNA in tissues (Figure 3D; Table 1).

Seven days later mice were systemically injected with LY379268, 3 mg/kg, i.p., and killed 24 h later.

Although DKO mice have systemically elevated 2-AG levels, CB2R-mediated signaling remains fully functional.