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Organs-on-a-chip have already proven to be a more effective tool than mice in some cases: Ingber's lung-on-a-chip, for example, illuminated a previously unknown connection between the human immune system and pulmonary edema, while another group from the University of California, Irvine, replicated human vasculature for insights into tumor metastasis and environmental-chemical toxicity.
In graduate school, I once found myself at a dinner with my friend and her brother, and when I mentioned that we used mice in some of our experiments, the brother pretty much lost his mind.
Before such monitoring, C57BL/6J mice in some production facilities developed significant genetic alterations.
There were differences in the intensity of the staining in different mice in some instances for the same marker.
It is an important clarification, since individual housing followed by social interaction drastically increases vocalization rate in mice in some paradigms.
Although we were able to determine H. trogontum colonization status by PCR in the majority of the mice, in some mice insufficient colonic tissue was available.
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Is it possible that he needs the mouse, in some disturbing way?
The metabolism of inorganic arsenic in human is different from rat and mouse in some aspects though the AS3MT has a high degree of similarity in these species.
Thymic cells, splenic cells, and pancreatic-infiltrating lymphocytes were obtained from a pool of mice, or in some experiments from individual mice.
Moreover, this maneuver resulted in complete absence of anti-mouse F9 and sustained expression of functional mouse F9 in some hemophilia B mice, particularly in those animals treated with the immunosuppressive drug cyclophosphamide.
Research conducted on mice in Oslo suggests some drugs could benefit athletes after their bans expire.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com