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Whereas, Sost KO mice had lower rBFR/BS relative to wild-type mice in high strain regions, but greater rBFR/BS relative to wild-type mice in low strain regions.
40% of the mice in high dosage PXF group and 80% of the mice in high dosage XF group were dead with severe kidney, liver, heart and lung morphology changes within the 7-day observation period.
However, intravenous administration of GO nanoflakes in mice in high concentration (4 mg/kg) for 5 consecutive days induced mutagenesis.
We examined mucosal EGFR activation (non-tumor area) by Western blotting and found that mice in high dose and low dose groups had increased mucosal EGFR phosphorylation.
For a closer behavioral analysis, we divided the group of rAAV-SHANK2-R462X-expressing rAAV-SHANK2-R462X-expressing rAAV-SHANK2-R462X-expressing rAAV-SHANK2-R462X-expressing
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We currently cannot explain the striking difference between WT and KO mice in high-grade lymphoma incidence and severity.
Our previous study shows that MALAT1 is significantly upregulated in the retinas of diabetic mice, in high-glucose-treated retinal endothelial cell line (RF/6A) or in the aqueous humor samples and fibrovascular membranes of diabetic patients.
Almost half of the tested chemicals caused tumors in either rats or mice in high-dose 2-year chronic/cancer bioassays (Martin et al. 2009a), with most of these having been determined by the U.S. EPA to be nongenotoxic tumorigens (U.S. EPA 2009).
Extract treatment had better role in female mice than in male mice, especially in high dose treatment (1 g/kg and 5 g/kg).
AZ-P7a cell line was established by repeated inoculation of the parental AZ-521 cells in mice, resulted in high peritoneal-metastatic potential [32], [33].
Male mice in the "high Al" group showed significant changes in light dark box tests and in various measures of behaviour in an open field.
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