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Mice were divided into four experimental groups with 8 mice in each of them: mice in control group received 50 µl diluent (PBS-DMSO); mice in second group received 50 µl free paclitaxel (300 ng/injection); mice in the third group received free paclitaxel (300 ng) and AMF/PGI (18 µg); and mice in group four received AMF/PGI-paclitaxel conjugate (300 ng of paclitaxel-equivalent and 18 µg of AMF/PGI).
Kidney function was detected by measuring the urea and creatinine levels in serum of pregnant mice in control and experimental groups.
One hour before the test, mice in control group and scop 1.5 mg group received distilled water and other mice were administered MEXX (50, 75, or 100 mg/kg, p.o).
In the test group treated with FMNPs, under external alternating magnetic field with 63 kHz and 7 kA/m for 4 min, the tumor tissues in gastric cancer-bearing mice grew slower than the mice in control group.
At 7 days post-injection, the nude mice in the test group and control group II were treated with alternating magnetic field with 63 kHz and 7 kA/m for 4 min once a week for 1 month, and the nude mice in control group I were not treated.
5 animals in sham group were fed just with normal food and water without any injection, 5 mice in control group were injected with 0.3 ml/day distilled water intraperitonealy, and 5 mice in 75 ppm group were injected with 0.3 ml/day NiNPs intraperitonealy for 1 week.
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We identified liver metastases in 8 of 9 mice in Control-group, 6 of 9 in HCS-L group and 5 of 9 in HCS-H group respectively.
Because BATF has been associated with reduced T-cell immunity, we wondered whether mice lacking BATF might have defects similar to IRF4-deficient mice in controlling viral infection.
Conversely, worm burden was higher in Nmur1-/ mice than in control mice.
111In-DTPA-cNGR and 99mTc-sestamibi dual-isotope SPECT imaging was performed 7 days post-ligation in MI mice and in control mice.
The uptake in the whole aorta was higher in LDLR -/- ApoB100/100 mice than in control mice, but the difference did not reach statistical significance.
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CEO of Professional Science Editing for Scientists @ prosciediting.com