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The highest titer of anti-BSA antibodies was detected in the blood serum of mice immunized simultaneously with BSA GNP and CpG GNP conjugates.
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As was observed with naïve mice immunized with CVB4/p24 733), CVB4-immune mice immunized with CVB4/p24 733) generated gag p24-specific immune responses.
Mice immunized with anti-DEC:OVA+anti-CD40 were protected, but mice immunized with PBS were not.
Simultaneously, THc (2 µg/well, 20 µg/mL) had been pre-incubated for 1h at 37 °C with sera from mice immunized with the different vaccines range from 50 µL to 0.4 µL/well.
Fig. 4 Serum responses in mice immunized with rOmpF.
The antiserum of mice immunized with chimeric viruses could neutralize various strains of HIV-1.
The antibody titers of the control mice immunized with PBS-adjuvant were only 1 30 1 100.
The main isotypes of antibody in mice immunized with Aβ-HBc VLPs were IgG1 and IgG2b, while isotype in mice immunized with Aβ1 42 was IgG2a.
Moreover, mice immunized with the uncleavable HA virus were protected against a challenge of lethal doses of influenza virus, unlike mice immunized with a formalin-inactivated virus.
Viral specific antibody-secreting cells presented high frequency in lung lymphocytes derived from mice immunized with IL-6 expressing adenovirus.
In addition, mice immunized with human gp100 demonstrated autoimmunity manifested as coat color depigmentation.
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