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In addition, 10 ovarian carcinomas established in nude mice have maintained a DNA content during serial passage similar to that of the original implanted tumour.
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Of interest, we have not observed T-cell tumors in Gli2ΔN2 transgenic mice, although we have maintained the colony for 3 years (N.J.R., unpublished observation, February 2004 to present).
Although these animals (rats, mice and monkeys) might have maintained an euthyroid state, the basis for hypothyroxinemia remained unclear.
The resultant patient-derived prostate tumor line used in our study, LTL163a, has been passaged for only 10 generations in immune-deficient mice and has maintained the original histopathological and genotypical characteristics of the original clinical sample [33], [34].
MaD1 mice have been maintained in our lab for over 17 generations using selection for high maternal defense.
Slo2.1 KO and Slo2.2 KO strains of mice have been maintained in a C57BL/6 background out to N = 12.
These mice have been maintained on a CBA × C57BL/6 background since their initial generation, full details of which can be found in Jennings et al. (2006).
For subjective roach and mice sightings, success was defined as having maintained zero pests at follow-up or having dropped a specified number of categorical responses.
He has maintained his innocence.
Charles River Laboratories (CRL) has genotyped microsatellite markers ("Max-Bax") to confirm that genetic variation in CD-1 mice has been maintained within their breeding facilities.
A colony of apoE−/ −, SOD2+/− mice has been maintained beyond 40 generations on the C57Bl/6 background at the University of Alabama Birmingham [for detailed description, see Supplemental Material (doi 10.1289/ehp.1002857)].
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