Sentence examples for mice have implicated from inspiring English sources
A series of studies that utilized in situ hybridization and mutant knockout characterizations in mice have implicated RORs in the context of skeletal, cardiorespiratory, and neurological development.
MMTV studies in mice have implicated FGF3, FGF4, FGF8 and FGF10 (reviewed in: [ 6, 21]) in mouse breast cancer development.
Studies in mice have implicated epidermal integrity, inflammatory responses and hyperplasia as key pathways in skin carcinogenesis (31– 31).
Similarly, studies of early-onset hearing loss in laboratory mice have implicated a number of genes in hearing function for the first time [ 13, 15].
For example, studies in mice have implicated a host of signalling pathways as being critical in proper tooth eruption and development, including those involving the gene families Bmp, Eda, Fgf, Shh and Wnt, among others (3– 5).
Furthermore, genetic studies in mice have implicated Slits and Robos in the targeting of OLF (Cho et al., 2007; Nguyen-Ba-Charvet et al., 2008) and VN (Cloutier et al., 2004; Prince et al., 2009) axons throughout development.
This situation has rapidly changed because new evidence from acquired and congenital forms of human scleroderma and Tsk/+ mice has implicated dysfunction of fibrillin-1 microfibrils in skin fibrosis [ 53].
Interestingly, recent studies in mouse have implicated CACNA1H activity in regular glomerulosa membrane potential oscillations that may amplify small changes in membrane potential to produce significant Ca2+ signals (Hu et al., 2012).
Both in vitro and in vivo knockout mouse studies have implicated TLRs in neointima formation and intimal hyperplasia involving modulation of inflammatory responses to exogenous and endogenous stimuli [14].
Knockout mouse studies have implicated several pro-apoptotic components of this pathway in B cell homeostasis.
Evidence suggests that SIRT1 also plays a fundamental role in the metabolism and differentiation of skeletal muscle cells [ 2], and transgenic or knockout Sirt1 mouse models have implicated the protein in protection of skeletal muscle against oxidative stress [ 3, 4].
