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Exact(5)
"So many times, the mice have failed us," the geneticist Nir Barzilai lamented.
"They are gorgeous studies, but they are in mice," he says, noting that a number of previous promising diabetes treatments that have worked in mice have failed to help human diabetics.
In addition, several studies of genetically modified mice have failed to demonstrate a clear effect of alteration of mitochondrial function on insulin action (4, 12).
Our attempts to interpret mechanistically our current data to understand more about the role of iRhom2 in EGFR signalling in mice have failed to lead to a clear model.
For example, in the subsection "Front-hind Interlimb coordination is specifically impaired in pcd", the authors mention that previous studies in ataxic mice have failed to detect any impairments in the kinematic parameters of individual limbs.
Similar(55)
Moreover, systemic administration of rotenone in C57BL/6J mice has failed to reproduce any of the pathological features of PD [33].
Targeted disruption of Cdc25C in mice has failed to reveal unique or compensatory functions for this family member under steady-state conditions.
Studies have shown that DRD2 gene knockout mice had failed to react to opioids reward [ 22], showing that DRD2 plays an important role in drug addiction.
Whereas this difference may reflect alternative methods for transplant conditioning, our analysis of WASp heterozygous mice has failed to identify any significant selective advantage for lineage-negative, hematopoietic stem cells or BM derived myeloid cells (A. Astrakhan and D.J.R., unpublished results, 2008).
A trap baited with a mouse had failed to catch the snake by Thursday, and the plane remained grounded.
Actually, Dr. Summerlin's efforts to graft skin from a black mouse onto a white mouse had failed, but he used a dark pen to make the experiment appear to be a success.
Related(20)
individuals have failed
studies have failed
ones have failed
backs have failed
livers have failed
birds have failed
mice have amassed
mice have had
mice have disorganized
mice have decreased
mice have sewn
mice have left
mice have suggested
mice have incorporated
mice have eaten
mice have displayed
mice have been
mice have puzzled
mice have shown
mice have forsaken
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com