Sentence examples for mice have developmental from inspiring English sources

This difference could explain why Dync2h1 mutant mice have developmental defects including polydactyly, while BBS mutant mice do not.

Female BAH knockout mice have developmental abnormalities and decreased fertility, and are more susceptible to tumour formation (Dinchuk et al, 2002).

Although total STAT3 deletion is embryonic lethal, these mice had developmental heart defects also suggesting an important role for STAT3 in cardiac development [24].

Because the atrial septum is closed when the lungs are inflated during birthing and because ASD manifests as a serious problem only after birth, we examined whether the HSP60 mice had developmental defects during the embryonic stage in the E17 embryos.

In summary, the Tbx22 null mouse has developmental defects similar to those found in patients with CPX and provides a new and unique model to understand the SMCP phenotype.

An important corollary to determining MEST function in adipose tissue expansion is that variation in diet-induced obesity in genetically identical adult mice could have developmental origins.

A study showed that Skp2−/− mice have specific developmental defects in the ovary (Fotovati et al, 2011).

Whereas Casp1 −/− mice have no developmental programmed cell death defects, they are protected against ischemic brain injury and heart failure.

Particularly, Cdkn1c has been implicated as a cyclin-dependent kinase that is active during embryogenesis, and Cdkn1c-/ mice have major developmental problems involving differentiation [ 46].

Like the RhoH-deficient mice, Zap70 null mice have a developmental block of the maturation at the double negative stage and peripheral thymocytes that are unresponsive to TCR mediated stimuli [ 66].

Similar to mice deleted with all p63 isoforms, ΔNp63-null mice have striking developmental defects including truncated forelimbs, the absence of hind limbs, and a lack of stratified epidermis [ 27].