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Rats and rhesus monkeys have been the primary animals used for actual space flight studies, but mice have also been utilized for studies in ground-based models.
The mouse disease is considered a good model of multiple sclerosis, but not perfect: some drugs that have worked in the mice have also worked in people, but others have not, and some proved harmful.
TAZ CKO mice have also been generated [123].
Agtr1A mice have also been useful in defining angiotensin responses that are mediated by receptors other than AT1A.
Proof-of-principle experimental studies utilizing knockin mice have also demonstrated that transgenic overexpression of the cardiac creatine transporter or the muscle CK isoform CKM can elicit marked protection against stress-induced heart injury.
The remains of mice have also been reported.
Transgenic mice have also been developed using a yeast artificial chromosome from this region (YAC 152F7).
Dph3 knockout mice have also been generated and are associated with lethality during embryonic life [43].
Furthermore, studies in young mice have also demonstrated selective iron accumulation in the white matter tracts[35].
Furthermore, homeostatically expanding cells in NOD mice have also been shown to rapidly acquire effector function [17].
Other studies performed in mice have also reported CSPG deposition post trauma using the same antibody [57].
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