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Though not a calorie counter, Yoda, like other dwarf mice, has a genetic mutation that chokes off production of growth and thyroid hormones.
We report here that thermoneutral housing of mice has a profound effect on the development of metabolic inflammation, insulin resistance, and atherosclerosis.
In particular, 4-MU in mice has a short half-life causing most of the drug to be present as the metabolite 4-methylumbelliferyl glucuronide (4-MUG), which makes it remarkable that 4-MU is effective at all.
Hyp mice have a disorder in phosphate homeostasis, and display hypo-mineralization in bones and teeth, while the Phex (phosphate regulating gene homologies to endopeptidase on the X chromosome) gene in Hyp mice has a deletion of the 3′ end.
The aim of this study was to characterize the tooth phenotype of CSF-1-deficient op/op mice and determine whether expression of csCSF-1 in these mice has a role in primary tooth matrix formation.
The first side-by-side look at tumor growth in mouse and human cells reveals an important imperfection in the mirror: A biochemical pathway with little influence on tumor growth in mice has a hefty impact in humans.
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Compulsive grooming in mice has an important ethological relevance.
Murphy Roth Large (MRL) mice have a remarkable regenerative capacity.
Therefore, mJNKKO mice have a muscle phenotype that mimics that of endurance trained athletes.
These mice had a simple injection, and the magnetic nanoparticles remained active a month later.
While homozygous Morg1−/− mice are embryonically lethal, heterozygous Morg1+/− mice have a normal phenotype.
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