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But vaccinated mice had dramatically fewer bacteria in their bodies compared with mice that received a dose of the carrier protein alone.
These mice had dramatically reduced cysts and significantly lowered numbers of trophic forms when compared to untreated controls.
These findings suggest that ICOS−/− mice had dramatically reduced T-mediated protection to re-infection compared to wild-type mice, associated with the reduced effector memory CD4 T cell population in ICOS−/− mice.
Multiple comparisons performed on OSS data revealed that heterozygous mice had a significant (p<0.05) elevation in responding relative to wildtypes, while knockout mice had dramatically blunted responding (p<0.001).
We noticed that the FoxN1TguCreERT+ juvenile mice had dramatically reduced mass of both the thymus and spleen, and absolute total cell number in both the thymus and spleen.
These mice had dramatically increased steady-state levels of MT-I mRNA and MT in the testes and in the female reproductive tract during the peri-implantation period of pregnancy, and this overexpression occurred in a cell-specific and temporally regulated manner similar to that of the endogenous MT-I gene.
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An German-American biochemist and expert in the 'quality-control' mechanisms that operate within the living cell, Dr. Walter is currently working on a "miracle" molecule that in early studies with brain damaged mice has dramatically improved brain function and restored memories.
Indeed, 4 6 week old p53 null mice have dramatically higher fractions of aneuploid cells in bone marrow, lymphoid and other tissues compared to normal mice [25], [26].
Excitingly, we found that the genetically modified SPAK mice have dramatically reduced blood pressure.
Using LDLR−/− mice, Rajavashisth et al. showed that atheroma development depends on M-CSF concentration, as not only did homozygous op/op mice have dramatically reduced lesions (∼0.3% of control lesion size) but heterozygous (op/+) mice had lesions <1% of controls.
Thus, through this endeavor the number of known metastable epialleles in the mouse has dramatically increased.
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