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After the CMS exposure, mice groups were administered with imipramine (IMP, 10 mg/kg, i.p).
Both mice groups were sacrificed on 5th day post-CHPV inoculation.
No significant differences among the different mice groups were found (Table 1).
On day 14 post laser induction (7 days post treatment) the sizes of CNV in all mice groups were measured, and also compared to original size of the CNV in mice 7 days post laser induction (untreated).
The methylation rates between tumor-bearing nude mice groups were analyzed using the Fisher's exact test.
Thirty days after mRNA immunization all mice groups were challenged with M. tuberculosis.
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The magnitude of the peak parasitemias between the different mice groups was not significantly different when comparing groups of mice infected with 105 or 104.
However, echocardiography demonstrated that systolic function in wild-type mice group were reduced after sepsis, while the cardiac function was relatively well persevered in cardiac-conditional deletion of Raptor (component of mTORC1 complex) mice group.
The cDNA probes from the tissue of control group were labeled with dCTP-Cy5, while those from the infected mice group were labeled with dCTP-Cy3.
Blood samples from all treated and control mouse groups were collected and centrifuged to obtain plasma samples.
Six-mouse groups were IN immunized twice at 4-week intervals (weeks 1 and 5).
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