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They observed an accelerated skin graft rejection in B.C.G. infected female C57BL/6 mice grafted with isologous male skin.
Intraperitoneal (ip) tumor burdens were reduced in athymic female mice grafted with human SKOV-3 ovarian adenocarcinoma cells and injected intravenously (iv) with curcumin-PEG.
Ultimately, similar techniques might also be applied to study other host parasite combinations, such as rodent parasites in their natural host (e.g., P. berghei Grammomys surdaster) or primate systems, or P. falciparum in humanized mice grafted with human cells or tissues24.
[11C]Erlotinib PET/CT scans were carried out in athymic nude mice grafted with subcutaneous (s.c).
This parameter also indicated enhanced recovery in mice grafted with L1 overexpressing SENAs compared to mice grafted with PBS, but only a tendency towards improved recovery when compared to mice grafted with wild-type SENAs six weeks after transplantation.
The linear density (number per unit length) of large perisomatic ChAT-positive boutons was increased in mice grafted with L1 overexpressing SENAs compared to mice grafted with wild-type SENAs or sham-injected with PBS (Fig. 6A, C).
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To investigate the role of C1q and C3 in graft rejection, we used a syngeneic model in which female mice were grafted with tail skin from syngeneic male mice and the rejection of the graft was monitored.
Nude mice were grafted with spontaneous primary MB from Ptch1+/− mice and treated every second day with s.c. injections of GlaB at a concentration of 75 μmol/kg or solvent only (n = 6 for each group).
Vascularized heterotopic cardiac transplantations were performed by standard microsurgical techniques and Balb/c (H-2d) mice were grafted with C57BL/6 (H-2b) hearts or C57BL/6 (H-2b) mice were grafted with Balb/c (H-2d) hearts according to the method of Corry [46].
In order to have a proper region for the background tissue, the mice were grafted with a single tumor on the left flank.
The mice were grafted with syngeneic male and female skin grafts 10 days later.
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