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For example, while lymphoma tumors merely grew more slowly in mice given either the drug rituximab or SIRPα proteins, the tumors virtually disappeared for at least 7 months in most mice treated with both drugs.
The serum levels of IL-6, IL-4, TNFα and IFNγ were found to be similar in mice given either PBS or DV-STM-07 (Figure 6).
Interestingly, although PI3Kγ has clearly been implicated in inflammation in many other systems [7], wild type mice given either wild type or PI3Kγ−/− bone marrow developed comparable M I/R injuries (Figure 3A, C) and showed equal Troponin T release (Figure 3D).
The mice given either of the two calcium channel inhibitors showed decreased levels of circulating creatine kinase and decreased necrosis in the diaphragm.
Measurement of fluorescent intensity from different areas in the striatal and caudate putamen region indicated that mice given either botanical diet had a significant decrease in p47phox immunoreactivity as compared with the ischemic group).
Mice given the booster of M2-DNA+M2-Ad hadramaticallyly greater M2e-PR8 specific IgG antibody responses than mice given either component alone (M2-DNA+B/NP-Ad or B/NP-DNA+M2-Ad; Figure 4A).
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To test whether anti-oxidant NAC can reduce adiposity in NPGPx-deficient mice, mice were given either regular drinking water or water supplemented with NAC.
In another experiment, mice were given either vehicle or amphetamine (2.5 mg/kg) for 5 days, and were then challenged with amphetamine (2.5 mg/kg) in combination with vehicle, SB 216641, or CP 94,253 on day 10.
NZB mice were given either PBS, or peptides 25 (241–251) and 29 (282–296) or both peptides intranasally on three occasions at 2-day intervals.
In a separate experiment tPA-deficient mice were given either mU1 (n = 9) or anti-TNP (n = 8) (60 mg/kg) and inflicted with a skin wound along the back mid-line, as described above.
Seven-week-old female BALB/cJ mice were given either 1 or 100 µg of each protein (i.e. KLH, BLG, Ara h 1 or Cry1Ab) by the i.p. or i.g. route at days 1 and 15 without any adjuvant (n = 5 per group, 200 µL/mouse).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com