Sentence examples for mice generated with from inspiring English sources

As a consequence, deleter mice generated with this improved FLPe are much less efficient compare to Cre deleter mice in terms of mediating recombination in vivo.

Tmub1 KO mice appeared normal in terms of weight, length and in a battery of physiological and metabolic assays (data not shown) routinely run on all mice generated with genetic deficiencies at Lexicon Pharmaceuticals [16].

Although we cannot exclude the possibility that our constructs bind to endogenous proteins and interfere with cellular physiology, we did not observe any abnormalities in the transgenic mice generated, with respect to cage behaviour, breeding performance and expression of marker proteins.

Finally, no detectable ß-actin signal was present in motor neuron cell bodies from a second line of ß-actin knock-out mice generated with the Nestin-Cre transgenic line (Figure S1A), which expresses Cre in motor neurons and other cells of the central nervous system (CNS-ActbKO) [35] [37].

Furthermore, primary cells cultured from patients with FGFR2 mutations and mice generated with the same mutations show differing proliferation and differentiation characteristics (reviewed in [ 22]).

The use of conditional transgenic mice and their proper controls or transgenic mice generated with ES cells may resolve this issue.

However, this was not the case for a mouse generated with the same 'mild' missense mutation (6589T>C in Mtco1) as two of our ES cell cybrids (33).

108 Mouse models have facilitated the progress in understanding the molecular pathogenesis of AS. 109 The Ube3a knockout mouse, generated with target disruption of Ube3a on the maternal chromosome 7, nicely recapitulates the human disorder.

Furthermore, targeting Brca1 loss of function to luminal cells in mice generated tumors with basal-like features that closely resembled those observed in patients carrying the BRCA1 mutation.

Injection of OTBCs in nude mice generated poorly differentiated breast carcinomas with colonization capabilities.

TCRβDMF transgenic mice were generated with the help of the mouse functional genomics Platform of the Marseille-Nice Genopole®.