(D) F0 generation of Tbx3-2A-GFP mice generated by eight-cell stage embryo injection (marked by red arrowheads).
Seven generations of crossing is considered acceptable for mice generated by a coisogenic strategy [21].
Dr. Lanza said that in serially cloned mice generated by other researchers the telomeres were getting longer at each generation.
Hochedlinger, K. & Jaenisch, R. Monoclonal mice generated by nuclear transfer from mature B and T donor cells.
Chen, J. et al. Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus.
Lee, J. H. et al. Differences between immunodeficient mice generated by classical gene targeting and CRISPR/Cas9-mediated gene knockout.
To visually examine beige adipocytes, we also utilized the beige-chaser mice generated by crossing Ucp1-Cre with Rosa26mT/mG mice.
Parikh, B. A., Beckman, D. L., Patel, S. J., White, J. M. & Yokoyama, W. M. Detailed phenotypic and molecular analyses of genetically modified mice generated by CRISPR-Cas9-mediated editing.
In addition to the analyses of naturally occurring mutations of the genes in humans, determination of the phenotypes of mice generated by genetic manipulation has been successful in clarifying the function of various gene products.
To further understand the role of synapsin I in the function of adult nerve terminals, we studied synapsin I-deficient mice generated by homologous recombination.
In the literature, there have been at least three lines of ACE2 knockout mice generated by gene targeting by different investigative groups.
