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These studies showed that mice generate multiple antibody specificities following exposure to F. tularensis [21], [22].
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Other groups have reported that luminal cells in both human and mouse mammary glands can generate multiple lineages of progeny when assayed in vitro [ 17, 54- 56].
Furthermore, the system could generate multiple Tg mice simultaneously.
The strategy provides the potential to generate multiple lines of mice, including an inducible allele, from a single targeting event for the cost of extra effort put into the planning stage of vector design.
Due to functional redundancy among the four members of the Id family and their widespread, overlapping expression patterns, only crosses between mice that lack different Id genes to generate multiple knock-outs are embryonic lethal.
The deletor mouse, although generating multiple deletions of the same range as proposed for mtDNA mutator mice, show no premature aging phenotype.
In MODEA model, multiple objectives generate multiple frontiers.
We then generate multiple paths for agents.
Alternative splicing can also generate multiple isoforms.
Both MI and bootstrapping generate multiple datasets.
Briefly, CD146floxed/floxed mice crossed with Tek+/Cre mice generate Tek+/CreCD146floxed/+ mice.
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