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To determine if C3d3 is an effective adjuvant for PA vaccination, we compared B cell immune responses in mice from several strains immunized with: PA-alum, PA-C3d3/IFA or PA in IFA.
In each test session, we analysed up to 24 mice from several different strains at once.
We added sequences amplified from genomic DNA of wild mice from several Eurasian sites to the data from inbred strains to generate nearest neighbour phylograms.
The discovery that mucosal delivery of Fc-fusions to Ags can protect mice from several viruses via FcRn provides urgent incentive to determine if such strategies are translatable to humans and non-viral pathogens, such as malaria and tuberculosis.
However, Desai et al. (1997) showed that an exercise test similar to the one utilized in the current study elicited heart rates near 750 beats per minute and a respiratory exchange ratio at or above 1.0 in mice from several inbred strains.
Mice from several litters were required to generate each experimental cohort; for quantitative transcriptional, pathological and immunohistochemical analyses, all cohorts were sex-matched and a maximum of one animal per genotype was used from a single litter.
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Evidence that nutritional deficiencies had little or no impact on the behavior of P2+P7 PCP mice come from several sources.
Both of these mice suffer from several neurological defects, including motor dysfunction, and exhibit progressive weight loss and brain atrophy.
For evolutionary comparisons, we compiled RNA-seq data containing mouse snRNAs from several types of cells and tissues (Table 1), including embryonic stem (ES) cells, differentiated ES cells, fetal head, cerebrum, and testis (Cui et al. 2010; Yang et al. 2011).
The Raman spectra of the live tumor model and of controlled mice were measured from several polyp-like tumors and from the control at different ages of up to 19 weeks.
After transplantation into immunodeficient mice, tumors form from several hundred marker-positive cells, whereas for marker-negative cells orders of magnitudes higher numbers are needed to achieve the same frequency of tumor formation (for a review: see [15].
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