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All mice from Experiments 1 3 were tested on spatial working memory (non-matching to place; NMTP [3]).
All mice (from Experiments 1, 2 and 3) were 8 12-weeks old at the start of 5-CSRTT training.
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Forty-eight hours after testing for investigation of a novel olfactory stimulus, mice from Experiment 5 were re-isolated into a clean cage and food-deprived during a 24-hr social isolation period.
After the experiment, a subset of mice from Experiment 2 were perfused for histological determination of the electrode placements (Fig. 3).
The 6 organs from 2 female BaP-treated (125 mg/kg/day for 5 days) and 2 corn oil-treated mice from Experiment 2 were used for analysis of miRNA expression.
The BPA dose administered to mice, from experiment 2C in which mice were fed a single 100,000 μg/kg dose of BPA, was scaled to the human dose multiplying the mouse serum-conjugated BPA values at each time point by a factor of 0.000693 (69.3/100,000 μg/kg).
Data are representative of six mice from two experiments.
Moreover, the control and doxycycline-treated mice included mice from previous experiments (Duivenvoorden et al, 2002).
Data are pooled from four to six mice from different experiments.
Data are representative of at least three mice from two experiments.
Sera (100 to 300 μl) from 29 mice from different experiments were extracted 3 times with 2.0 ml ether/chloroform (6:1).
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