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Results indicate that mutant mice expressing lower HO-1 had fewer lung metastases compared to mice expressing normal HO-1.
Experiments conducted in mice with Plasmodium yoelii, a murine model for parasite sequestration, seem to support such a hypothesis: in one study, while transgenic mice expressing high HbS proportions developed low parasitemia infections and recovered completely, mice expressing lower levels of HbS experienced severe infections and died (Hood et al., 1996).
Mice expressing lower levels of miR-499 (line #17 or TG-17) appeared normal under basal conditions (n = 20).
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STRA13 KO mice express lower levels of Rae-1 transcripts than the control mice and their expression is not circadian [10].
The Tg6F-fed mice expressed lower levels of TNFα, iNOS, and TGFβ compared to chow-fed mice, in both jejunum and lung (Fig. 2a,b).
First, we hypothesized that Tph1 mice express lower levels of SERT than WT controls.
Interestingly, the mutant mice expressed lower basal levels of Slfn4 in BMM.
Similarly, BDC2.5 T cells that migrated to the pancreatic lymph nodes of anti-GITRL antibody-treated mice expressed lower levels of CD69 (figure 9B).
We postulated that: 1) Tph1 mice express lower levels of pulmonary 5-HT transporter (SERT) when compared to wild-type controls, and 2) Tph1 mice display adaptive changes in the expression of non-serotonergic pulmonary genes which are implicated in PAH.
Importantly, embryonic fibroblasts from basigin-deficient mice expressed lower levels of HAS2 than wild-type fibroblasts.
Recently, it was shown that DCs from older mice express lower CD86 in vivo relative to DCs from younger mice (Chiu et al., 2007).
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