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In that study, LKB1 floxed mice were crossed to mice expressing a RIP2-promoter driving Cre-recombinase expression.
Mice heterozygous for the conditional allele (Pik3c3flox/+) [32], [32] were bred with mice expressing a Meox-cre transgene with cre expressed in the germ line to generate Pik3c3+/− animals.
In mice expressing a single TCR specific for a non-self-antigen, no Treg develop.
These mice express a nonmuscle isoform of the myosin light chain kinase gene (nmMLCK2) targeted to the endothelium.
The function of the UPS was assessed in vivo by crossing our mice with UbG76V-GFP transgenic mice, expressing a UPS reporter substrate.
To investigate the role of Angpt1-Tie2 sinnaling in hematopoiesis, we prepared conditionally inducible transgenic (Tg) mice expressing a genetically engineered Angpt1, cartridge oligomeric matrix protein (COMP -Angpt1.
We evaluated the behaviour of mice expressing a dominant negative, neuron-specific mutation of TRα (TRαAMI/Cre3 mice), using the elevated-plus maze, light-dark box and open-field tests.
Conversely, mice expressing a truncated mouse EpoR were not polycythemic [11].
A similar bone marrow phenotype was reported in mice expressing a deletion mutant FosB transgene [57].
Transgenic mice expressing a construct harboring the 3'UTR of versican exhibits the adhesion of organs.
We produced transgenic mice expressing a lacZ reporter controlled by the intronic promoter.
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