By contrast, juvenile BALB mice expressed a substantially lower SCPP response (Fig. 2b′; F3,109= 4.2, P= 0.008), exploring the two conditioning environments to a similar extent (t= 1.0, df = 23, P= 0.84).
The latter expressed substantially truncated versions of the 33-mer (Fig. S2).
In addition, ML-II chondrocytes expressed substantially higher levels of type II collagen.
Compared to LPS-matured BMDCs from A/J mice, those from C3H mice expressed slightly less MHC Class II and CD86 and substantially less CD80 (Figure 7a), likely the result of impaired LPS-induced maturation resulting from the lack of functional TLR4 in C3H mice [49].
Mutant mice expressed both wild-type and mutant decorin.
Bax−/− mice expressed no detectable BAX protein.
Tnc− / − mice expressed significantly less miR-155 than tnc +/+ mice.
Tfh cells express substantially lower levels of T-bet, and instead of Blimp1 they express the TF Bcl6.
Marrow derived from mice expressing only this receptor generate substantially more osteoclasts in response to the cytokine than do the wild type, whereas those bearing only the other TNF receptor, p75r, produce fewer [ 77].
The recent report that KRAS-induced pancreatic cancer was substantially reduced in mice expressing an S6 mutant that could not be phosphorylated also highlighted the importance of this signalling arm downstream of mTOR.
