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Lung tissue of mock infected mice expressed only the epithelial marker, thyroid transcription factor-1 (TTF-1), in the nuclei of alveolar epithelial cells.
Hearts of Ltbp4S−/− mice expressed only Ltbp4L mRNA.
SVs from control mice expressed only the full-length (WT) band, whereas SVs from PTM-ARKO mice expressed both the WT and smaller KO band (data not shown).
In contrast with the lung, sorted γδ T cells from the draining LN of naive (n = 3 pools of three to six mice) and S. pneumoniae-challenged mice (n = 3 pools of three to six mice) expressed only Vγ1, Vγ2 and, weakly, Vγ4 mRNA (Fig. 1B).
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But, cells that show DNA-recombination co-expressed NCre and CCre, since in mice expressing only either NCre or CCre no recombination could be observed.
ZNF148 (alias ZBP89) was originally reported as a gastrin gene expression repressor [28], [29] and recently, studies of mice expressing only ZBP89-delta-N showed significant growth delay and a reduction of viability [30].
We show that DAT-KO/HAD-Tg mice express only 8.5% of WT DAT levels in the striatum.
We have used genetically engineered NMDA receptor NR1+/− mice in which the gene for the NR1 subunit was modified in such a way that these mice express only 50% of the NR1 subunit.
Bred to a Ptbp2 knockout, the transgene allowed us to compare the developmental and molecular phenotypes of mice expressing only PTBP1, only PTBP2, or neither protein in the brain.
A similar argument applies to mice expressing only the L pigment.
APPPS1 mouse model expresses 'Swedish' mutant APP and M146L mutant presenilin [28] whereas R1.40 mice express only 'Swedish' mutant APP [29].
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