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Voss et al. noted that ch14.18 mAbs labeled with 64Cu through the extremely stable SarAr chelator for PET imaging of neuroblastoma or melanoma xenografts in mice exhibited low liver uptake (5%to10%0% i.d./g) but no comparison with other chelators was provided [31].
Both control ASO and DEP-1 ASO mice exhibited low RER values.
Transgenic mice exhibited low, intermediate, or high HCV core protein expression when fed a permissive diet of standard chow.
In contrast, the T1r3 KO mice exhibited low and statistically indistinguishable rates of licking for each sugar solution and water (in all comparisons, paired t-values were <1.9, df = 8, P > 0.10).
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We speculated that aging might act as a chronic stimulus and investigated whether Siglec-E−/− mice exhibited low-grade signs of inflammation.
At an early age, these mice exhibit low levels of soluble Aβ40 and Aβ42 in their brains, and the levels increase significantly by 12 months.
Whereas untreated BlaJ mice exhibit low levels of pathology at the time point studied, significant differences in fibers with centralized nuclei were calculated for the gastrocnemius muscle for both low and high dose treated animals.
Accordingly, published data demonstrate that ATGL-deficient mice exhibit low plasma FA levels, improved glucose tolerance and insulin sensitivity, and are resistant to high-fat diet-induced insulin resistance.
Consisting with the above hypothesis, we showed that vehicle-treated WBH mice exhibiting lowest survival showed the lowest plasma ACTH and corticosterone levels.
After 8 weeks, rDer p 1-treated mice already exhibited low levels of antigen-specific IgG1 antibodies (Fig. 1a).
In the series of the gravid mice analyzed in this study we came across a gravid mouse that exhibited low fluorescence signal at 12.5 dpc) as compared to age-matched control gravid mice).
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