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Indeed, 3xTg-AD mice exhibited frequent short episodes of low activity.
αMHC-Cre::VHL fl/fl mice exhibited frequent cardiac arrhythmia, consistent with sudden cardiac death, as did hypoxic wild-type mice (Fig. 3).
Perp null mice exhibited frequent basal-suprabasal blistering in the skin and oral cavity (47), and developed ectodermal dysplasia and palmoplantar keratoderma (67).
We next found that the 20-week-old mixed strain mice exhibited frequent neovascularisation or plaque hemorrhage as well as macrophage infiltration, findings that were exacerbated by chronic stress (Fig. 5).
Particularly, both MEFs and glomerular cells derived from Nlp transgenic mice exhibited frequent centrosome amplification, suggesting that Nlp overexpression is tumour prone, which mimics BRCA1 loss in vivo (Xu et al, 1999).
Similar(55)
MSCs from Artemis-deficient mice exhibited more frequent double-strand breaks, translocations and fragmentations than did their WT littermates, yet retained a normal growth rate and ability to differentiate along the usual trilineage pathways.
Histopathologic analyses of tumors from 5αP-treated mice showed hypercellular solid carcinomas invading the muscle and other outer aspects of the thoracic cavity and exhibited frequent mitoses.
The child exhibited frequent random multifocal myoclonic movements of his extremities.
Some hypervariable regions also exhibited frequent and extensive insertions and deletions (INDELS).
Dinucleotide microsatellites exhibited frequent instability (40/318; 12.58%) compared to mononucleotide microsatellites (13/212; 6.13%) (data not shown).
In the second postnatal week, however, both male and female LGI1−/− mice began to exhibit frequent spontaneous seizures.
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