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Upon Ets1 induction in differentiating cells of stratified squamous epithelium, these mice exhibited dramatic changes in epithelial organization including increased proliferation and blocked terminal differentiation.
In response to oral exposure to TCDD, sensor mice exhibited dramatic and sustained activation of AhR.
After PAB, Fn14+/+ mice exhibited dramatic increases in RV end-systolic volume (ESV) and end-diastolic volume (EDV), indicating dilation and a decrease in RV ejection fraction (EF).
Furthermore, livers harvested from Ifnar1 SA mice exhibited dramatic histopathologic alterations (Fig 5C and Supplementary Fig 16) along with robust activation of p38 kinase (Fig 5D), greater number of hepatic lesions and consistently higher hepatitis grade (Table 1).
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As shown in Figure 1A D and Supplementary Material, Table S1, and as we reported previously, F66 transgenic mice exhibit dramatic increases in skeletal muscle mass throughout the body.
These results contrasted markedly with the subclass distribution of PsaA-BLyS immunized mice, which exhibited dramatic elevations for IgG1, IgG2a, IgG2b and IgG3 subclasses.
Furthermore, Dicer-deficient mice exhibited a dramatic reduction in blood pressure due to significant loss of vascular contractile function and SMC contractile differentiation as well as vascular remodeling.
As expected, ChR2-expressing mice exhibited a dramatic avoidance of the photostimulation chamber during the training period, as compared to eYFP controls.
In these and previous experiments, Mcl-1f/fLckCre micexhibiteded a dramatic reduction (~90%) in total thymocyte number due to a block at DN, specifically, an accumulation at the CD44+CD25+ DN2 and CD44−CD25+ DN3 stages.
22 Abca12-/ skin grafts kept in a dry environment exhibited dramatic improvements in all the abnormalities seen in the model mice.
Transgenic rainbow trout overexpressing FST exhibited dramatic muscularity (Medeiros et al. 2009).
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