Interestingly, TIMP4 was found not to contribute to cardiac response to mechanical stress, as TIMP4−/− mice exhibited comparable cardiac remodeling, dysfunction and myocardial fibrosis compared with the parallel wildtype mice [ 141].
Finally, while C57BL/6 and 129/Sv mice exhibited comparable behavior during FR1 sessions, C57BL/6 mice tended to acquire food-maintained responding faster than 129/Sv counterparts, and exhibited elevated responding during PR testing.
DG/Lck-cre mice exhibited comparable LCMV specific IFN-γ expressing CD4+ and CD8+ T cells to that of littermate controls (Fig. 5E).
The mutant and control mice exhibited comparable performances in quadrant occupancy (Figure 5E), target quadrant occupancy (Figure 5F), and the number of platform crossings (Figure 5G).
Conclusions Sirt1Tg and WT littermate mice exhibited comparable acute histopathological reactions to the systemic injection of MPTP, loss of TH-positive neurons and reactive gliosis.
At the 8-week time point prior to TAM-induced NELF-B deletion, the KO mice exhibited comparable LV function as the control littermates.
Accordingly, isolated APCs from pLNs of sham-treated and injured mice exhibited comparable ability to induce OVA-specific Th-cell proliferation (Supplementary Figure S2C) and IFN-γ secretion in vitro (Supplementary Figure S2D).
A preferential accumulation of radioactivity was observed in the inflamed extremities of mice injected with SIP L19) and SIP(G11), whereas no preferential antibody accumulation could be detected in mice exhibiting comparable grades of inflammation that had been injected with a SIP antibody of irrelevant specificity in the mouse.
The special relevance of MSH2/MSH6 in B cells is further evidenced by the findings that mice deficient in either MSH2 or MSH6 exhibit comparable decreases in CSR and losses of mutations at A T bases [11] [15].
Nevertheless, all three retro-peptides exhibit comparable ribonuclease activity [Fig. 2].
