A total of 210 units with clear spike waveforms were recorded from these 24 mice (for examples of well-isolated units, see Figure S1).
For example, a mouse model of HGPS that is deficient for ZMPSTE24 exhibits aneuploidy in up to 40% of cultured cells [22].
For example, a mouse model of H. pylori-induced gastritis, Th cells were found to be both 'necessary and sufficient' for the development of H. pylori-associated gastritis.
For example, one mouse model of dependence and relapse drinking has demonstrated that repeated cycles of chronic alcohol exposure delivered by inhalation result in an escalation of voluntary alcohol drinking (Becker and Lopez 2004; Lopez and Becker 2005).
For example, in the mouse model of multiple sclerosis, in vivo neutralization of IFN-γ resulted in exaggerated immune response and central nervous system immunopathology [27].
For example, in a mouse model of collagen-induced arthritis, treatment of mice with sRAGE significantly reduced synovial inflammation, as well as cartilage and bone destruction [ 5].
For example, in a mouse model of neurodegenerative disease, blood biomarkers have been shown to allow pre-symptomatic diagnosis and analysis of the stage of disease progression [ 62].
For example, in the mouse model of Saito et al. where Aβ43 is overproduced because of a mutation, the ability of an Aβ43-specific immunotherapy to prevent both plaque formation and the observed neurological deficits could be tested.
For example, in a mouse model of hemorrhagic EBOV infection, a vesicular stomatitis virus-based vaccine has been shown to be safe and effective in preventing clinical presentation of disease (151).
For example, in a mouse model of direct (intra-tracheal endotoxin) and indirect (intra-peritoneal endotoxin) lung injury, Menezes et al. observed higher pulmonary IL-6, TNF-α mRNA and cellularity in bronchoalveolar lavage fluid in the former.
